2002

研究業績

Papers (English)

Original papers

1. Grammas P, Yamada M, Zlokovic B. The cerebromicrovascularture: a key player in the pathogenesis of Alzheimer’s disease. J Alzheimer Dis 4:217-223, 2002

2. Hasegawa K, Ono K, Yamada M, Naiki H. Kinetic modeling and determination of reaction constants of Alzheimer’s beta-amyloid fibril extension and dissociation using surface plasmon resonance. Biochemistry 41:13489-13498, 2002

3. Ishibashi S, Yokota T, Shiojiri T, Inaba A, Iwai I, Yamada M, Mizusawa H. Mexiletine is effective on segmental hyperhidrosis. Report of two cases. J Neurol Neurosurg Psychiatry 72: 112, 2002

4. Nanri K, Utsumi H, Yamada M, Takada Y, Matsumura A, Kougo K, Sekine S, Ogawa D,
Toyoda M. Transthyretin Val 107 in a Japanese pateint with familial amyloid polyneuropathy. J Neurol Sci 198:93-96, 2002

5. Nishida Y, Yamada M, Hara K, Tsunemi T, Yamawaki M, Shimokawa R, Okeda R, Tsutsumi T, Mizusawa H. Creutzfeldt-Jakob disease after Janneta’s operation with cadaveric dura mater graft: initial manifestations related to the gfafted site. J Neurol 249: 480-483, 2002

6. Ono K, Hasegawa K, Yamada M, Naiki H. Nicotine breaks down preformed Alzheimer’s β-amyloid fibrils in vitro. Biol Psychiatry 52:880-886, 2002

7. Ono K, Hasegawa K, Yoshiike Y, Takashima A, Yamada M, Naiki H. Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer’s β-amyloid fibrils in vitro. J Neurochem 81:434-440, 2002

8. Ono K, Komai K, Yamada M. Myoclonic involuntary movement associated with chronic manganese poisoning. J Neurol Sci 199:93-96, 2002

9. Yamada M. Risk factors for cerebral amyloid agniopathy in the elderly. Ann N Y Acad Sci 977:37-44, 2002

10. Yamada M, Sodeyama N, Itoh Y, Suematsu N, Otomo E, Matsushita M, Mizusawa H. No association of paraoxonase genotype or atherosclerosis with cerebral amyloid angiopathy. Stroke 33:896-900, 2002

Book

1. Yamada M. Cerebral amyloid angiopathy: clinicopathological features with molecular basis. In: Sinha KK, Chandra P, ed. Advances in Clinical Neuroscience, Vol. 12, Catholic Press, Ranchi, pp193-217, 2002

Presentations (International meeting)

Invited lectures

1. Yamada M. Risk factors for cerebral amyloid angiopathy in the elderly. The 3rd World Congress on Vascular Factors in Alzheimer’s disease. Kyoto, April 7 – 10, 2002

2. Yamada M. Pathomechanisms of Neuromuscular Disorders in AL and TTR amyloidoses. The 5th International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders. Matsumoto, September 24-27, 2002

3. Yamada M. Risk factors for sporadic cerebral amyloid angiopathy in the elderly. The 2nd International Conference on Cerebral Amyloid Angiopathy (CAA). Newcastle upon Tyne, UK, December 4 – 6, 2002

Presentations

1. Ono K, Yamada M, Hasegawa K, Naiki H. Nordihydroguaiaretic acid potently breaks down preformed Alzheiemer’s b-amyloid fibrils in vitro. The 8th International Conference on Alzheimer’s Disease and Related Disorders. Stockholm, July 20-25, 2002

2. Yamada M, Sodeyama N, Mizusawa H, Itoh Y, Takahashi A, Otomo E, Matsushitqa M. Risk factors for sporadic cerebral amyloid angiopathy. The 8th International Conference on Alzheimer’s Disease and Related Disorders. Stockholm, July 20-25, 2002