2008

研究業績

Papers (English)

Original papers

1. Chen W, Samuraki M, Yanase D, Shima K, Takeda N, Ono K, Yoshita M, Nishimura S,
Yamada M, Matsunari I. Effect of sample size for normal database on diagnostic performance of brain FDG PET for detection of Alzheimer’s disease using automated image analysis. Nucl Med Commun 29:270-276, 2008

2. Das RR, Seshadri S, Beiser AS, Kelly-Hayes M, Au R, Himali JJ, Kase CS, Benjamin EJ, Polak JF, O’Donnell CJ, Yoshita M, D’Agostino RB Sr, DeCarli C, Wolf PA. Prevalence and correlates of silent cerebral infarcts in the Framingham offspring study. Stroke 39:2929-2935, 2008

3. Furukawa Y, Yoshikawa H, Iwasa K, Yamada M. Clinical efficacy and cytokine network-modulating effects of tacrolimus in myasthenia gravis. J Neuroimuunol 195:108-125, 2008

4. Hamaguchi T, Fuisawa H, Sakai K, Okino S, Kurosaki N, Nishimura Y, Simizu H, Yamada M. Acute encephalitis caused by in intrafamilial transmission of enterovirus 71 in adult. Emerg Inf Dis 14:828-830, 2008

5. Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Nakamura Y, Sato T, Kitamoto T, Mizusawa H, Yamada M. Medical procedures as risk of sporadic Creutzlfedt-Jakob disease. Emerg Inf Dis 15:265-271, 2009

6. Hamaguchi T, Yamada M. Basiparallel anatomic scanning-magnetic resonance imaging in vertebral artery dissection. Arch Neurol 66:276-277, 2009

7. Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Nakamura Y, Sato T, Kitamoto T,　Mizusawa H, Yamada M. The risk of iatrogenic Creutzfeldt-Jakob disease through medical and surgical procedures. Neuropathology 29:625-631, 2009

8. Hirohata M, Ono K, Morinaga A, Yamada M. Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for α-synuclein fibrils in vitro. Neuropharmacology 54:620-627, 2008

9. Hirohata M, Ono K, Morinaga T, Ikeda T, Yamada M. Anti-aggregation and　fibril-destabilizing effects of sex hormones on alpha-synuclein fibrils in vitro. Exp Neurol 217:434-439, 2009

10. Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow DB, Humala N, Cheng A,
Percival SS, Ferruzzi M, Janle E, Weaver C, Dickstein DL, Pasinetti GM. Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer’s disease-type neuropathology and cognitive deterioration. J Alzheimers Dis 16:59-72, 2009

11. Ikeda Y, Abe K, Ishida C, Takahashi K, Hayasaka K, Yamada M. A clinical phenotype of distal hereditary motor neuronopathy type II with a novel HSPB1 mutation. J Neurol Sci 277:9-12, 2009

12. Ishida C, Makifuchi T, Saiki S, Hirose G, Yamada M. A neuropathological study of autosomal dominant chorea-acanthocytosis with a mutation of VPS13A. Acta Neuropathol 117:85-94, 2009

13. Ishida C, Saiki S, Yamada M. Reply: Chorea-acanthocytosis with an autosomal-dominant trait. Acta Neuropathol 117: 97-98, 2009

14. Kato-Motozaki Y, Ono K, Shima K, Morinaga A, Machiya T, Nozaki I, Shibata-Hamaguchi A, Furukawa Y, Yanase D, Ishida C, Sakajiri K, Yamada M. Epidemiology of familial amyloid polyneuropathy in Japan: Identification of a novel endemic focus. J Neurol Sci 270:133-140, 2008

15. Kato-Motozaki Y, Komai K, Takahashi K, Ishida C, Ueda M, Kusunoki S, Yamada M. Polyethylene glycol interferon α-2b-induced immune-mediated polyradiculoneuropathy. Intern Med 48:569-572, 2009

16. Kojima.Y, Sakai K, Ishida C, Asaka T, Hamaguchi T, Nozaki I, Fukushima K, Tsuchiya A, Kametani F, Yazaki S, Yamada M. Hereditary rimmed vacuole myopathy showing interstitial amyloid deposition in muscle tissue. Muscle Nerve 40:472-475, 2009

17. Maruta T, Yoshikawa H, Fukasawa S, Umeshita S, Inaoka Y, Edahiro S, Kado H, Motozaki Y, Iwasa K, Yamada M. Autoantibody to dyhydropyridine receptor in myasthenia gravis. J Neuroimmunol 208:125-129, 2009

18. Matsumoto Y, Yanase D, Noguchi-Shinohara M, Ono K, Yoshita M, Yamada M. CSF/serum IgG index is correlated with medial temporal lobe atrophy in Alzheimer’s disease. Dement Geriatr Cogn Disord 25:144-147, 2008

19. Nakamura Y, Uehara R, Watanabe M, Sadakane A, Yamada M, Mizusawa H, Maddox R,
Sejvar J, Belay E, Schonberger L. Update: Creutzfeldt-Jakob disease associated with cadaveric dura mater grafts―Japan, 1979 – 2008. MMWR 57:1152-1154, 2008

20. Noguchi-Shinohara M, Tokuda T, Yoshita M, Kasai T, Ono K, Nakagawa M, El-Agnaf OMA, Yamada M. CSF α-synuclein levels in dementia with Lewy bodies and Alzheimer’s disease. Brain Res 1251:1-6, 2009

21. Noto D, Takahashi K, Hamaguchi T, Inamura K, Nobata K, Yazaki M, Ikeda S, Kobayashi K, Yamada M. A case of adult onset type II citrullinemia with portal-systemic shunt. J Neurol Sci 281:127-129, 2009

22. Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB. Effects of grape seed-derived polyphenols on amyloid β-protein self-assembly and cytotoxicity. J Biol Chem 283:32176-32187, 2008 This paper was selected as “JBC paper of the week”.

23. Sakai K, Tada M, Yonemochi Y, Nakajima T, Onodera O, Takahashi H, Kakita A. Marinesco-Sjögren syndrome with atrophy of the brain stem tegmentum and dysplastic cytoarchitecture in the cerebral cortex. Neuropathology 28:541-546,2008

24. Samuraki M, Komai K, Hasegawa Y, Kimura M, Yamaguchi S, Terada N, Yamada M. A successfully treated adult patient with L-2-hydoxyglutaric aciduria. Neurology 70:1051-1052, 2008

25. Samuraki M, Nakahashi T, Aoyama S, Hinoue Y, Takahashi H, Saito K, Hayashi S. Liver sarcoidosis that presented with dysphagia. Intern Med 47:1259-1261, 2008

26. Samuraki M, Hayashi S. The author reply: acute renal failure as the first extrapulmonary presentation of sarcoidosis. Internal Med 47:2203, 2008

27. Seshadri S, Wolf PA, Beiser AS, Selhub J, Au R, Jacques PF, Yoshita M, Rosenberg IH, D’Agostino RB, DeCarli C. Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Arch Neurol 65:642-649, 2008

28. Shibata-Hamaguchi A, Ishida C, Kitagawa S, Yamada M.Peripheral and multiple cranial neuropathies in a 74-year-old woman. Neuropathology 28:448-451, 2008

29. Shibata-Hamaguchi A, Ishida C, Iwasa K, Yamada M. Prevalence of spinocerebellar degenerations in the Hokuriku district, Japan. Neuroepidemiology (In Press)

30. Shima K, Ishida C, Okino S, Kotani T, Higashi K, Yamada M. A linear lesion along the brachial plexus on FDG-PET in neurolymphomatosis. Intern Med 47:1159-1160, 2008

31. Takamori M. Autoantibodies against TRPC3 and ryanodine receptor in myasthenia gravis. J Neuroimmunology 200:142-144, 2008

32. Takamori M. Lambert-Eaton myasthenic syndrome: Search for alternative autoimmune targets and possible compensatory mechanisms based on presynaptic calcium homeostasis. J Neuroimmunology 201-202:145-152, 2008

33. Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, Humala N, Teplow DB, Pasinetti GM. Grape seed extract MegaNatural-AZ prevents Aβ oligomerization and attenuates cognitive deterioration in a mouse model of Alzheimer’s disease. J Neurosci 28:6388-6392, 2008

34. Wright CB, Festa JR, Paik MC, Schmiedigen A, Brown TR, Yoshita M, DeCarli C, Sacco R,
Stern Y. White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibility. Stroke 39:800-805, 2008

35. Wu W, Brickman AM, Luchsinger J, Ferrazzano P, Pichiule P, Yoshita M, Brown T, DeCarli C, Barnes CA, Mayeux R, Vannucci SJ, Small SA. The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life. Ann Neurol 64:698-706, 2008

36. Yamada M, Noguchi-Shinohara M, Hamaguchi T, Nozaki I, Kitamoto T, Sato T, Nakamura Y, Mizusawa H. Dura mater graft-associated Creutzfeldt-Jakob disease in Japan: Clinicopathological and molecular characterization of the two distinct subtypes. Neuropathology 29:609-618, 2009

37. Zhao W, Wang J, Ho L, Ono K, Teplow DB, Pasinetti GM. Identification of antihypi GM. Identification of antihypertensive drugs which inhibit amyloid β-protein oligomerizationertensive drugs which inhibit amyloid β-protein oligomerization. J Alzheimers Dis 16:49-57, 2009

Reviews

1. Hirohata M, Ono K, Yamada M. Non-steroidal anti-inflammatory drugs as anti-amyloidogenic compounds. Curr Pharm Design 14:3280-3294, 2008

2. Nakajima K, Yoshita M, Matsuo S, Taki J, Kinuya S. Iodine-123-MIBG sympathetic imaging in Lewy-body diseases and related movement disorders. Q J Nucl Med Mol Imaging 52:378-87, 2008

3. Ono K, Hirohata M, Yamada M. α-synuclein assembly as a therapeutic target of Parkinson’s disease and related disorders. Curr Pharm Design 14: 3247-3266, 2008

4.Takamori M. Lambert-Eaton myasthenic syndrome:Search for autoimmune targets and possible compensatory mechanisms based on presynaptic calcium homeostasis. J Neuroimmunology 201-202:145-152, 2008

5. Yamada M. Editorial: Anti-amyloidogenic/protein-misfolding therapies in amyloidosis and other protein-misfolding disorders. Curr Pharm Design 14:3203-3204, 2008

6. Yamin G, Ono K, Inayathullah M, Teplow DB. Amyloid β-protein assemblys as therapeutic target of Alzheimer’s disease. Curr Pharm Design 14: 3231-3246, 2008

Executive Editor

Current Pharmaceutical Design
Volume 14, Number 30, 2008
Hot Topic Issue: “Anti-Amyloidogenic/Protein-Misfolding Therapies in Amyloidosis and Other Protein-Misfolding Disorders” (Executive Editor:Masahito Yamada)

Presentations (International meeting)

Invited lectures

1. Ono K, Teplow DB. Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. First Annual Meeting and Symposium “Protective Roles of Crape-Derived Polyphenols in Alzhimer’s Disease. West Lafayette, Sep 29-30, 2008

2. Takamori M. Non-voltage-gated calcium channel antibodies in Lambert-Eaton myasthenic Societies. The 12th Congress of the European Federation of Neurological Societies. Madlid, August 23-26, 2008

3. Yamada M, Nakamura Y. CJD surveillance in Japan. European and Associated Countries Collaborative CJD Surveillance Group. Riga, May 29-31, 2008

4. Yamada M. Cerebral amyloid angiopathy at the cross roads of stroke and dementia. UCLA Medical Center Seminar, Los Angeles, July 25, 2008

5. Yamada M. Cerebral Amyloid Angiopathy: Epidemiology, Clinical Features and Genetic Risk Factors. The 11th International conference on Alzheimer’s disease and Related
Disorders, Chicago, July 26-31, 2008

Presentations

1. Carmichael OT, Drucker D, Fletcher E, Ortega M, He J, Yoshita M, DeCarli C. MRI Measures of Cerebrovascular Disease in the Alzheimer’s Disease Neuroimaging Initiative. The 60th Annual Meeting of American Academy of Neurology, Chicago, April 17, 2008

2. Carmichael OT, Drucker D, Fletcher E, Ortega M, Yoshita M, He J, DeCarli C. MRI Measures of Cerebrovascular Disease in the Alzheimer’s Disease Neuroimaging Initiative. The 11th International Conference on Alzheimer’s Disease and Related Disorders (ICAD2008), Chicago, July 26-31, 2008

3. Carmichael OT, Drucker D, Schwarz C, Fletcher E, Martinez O, Yoshita M, He J, DeCarli C. Longitudinal changes in cognition and cerebrovascular disease in the Alzheimers disease neuroimaging initiative. The 11th International Conference on Alzheimer’s Disease and Related Disorders (ICAD2008), Chicago, July 26-31, 2008

4. Cheng A, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow DB, Humala N, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM, Ho L. Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer’s Disease-type neuropathology and cognitive deterioration. Neuroscience 2008, Washington DC, Nov 15-20, 2008

5. Hamaguchi T, Noguchi-Shinohara M, Nakamura Y, Sato T, Kitamoto T, Mizusawa H, Yamada M. Medical procedures and sporadic Creutzfeldt-Jakob disease: analyses with the Japanese CJD surveillance. PRION 2008, Madrid, Oct 8-10

6. Hirohata M, Ono K, Morinaga A, Yamada M. Non steroidal anti inflammatory drugs have potent anti α-synuclein fibril effects in vitro. The 11th International Conference on Alzheimer’s Disease and Related Disorders (ICAD2008), Chicago, July 26–31, 2008

7. Ho L, Ksiezak-Reding H, Ono K, Yemul S, Humala N, Cheng A, Pfleger C, Wang J, Teplow DB, Pasinetti GM. Grape seed polyphenolic extract (GSPE) as a novel therapeutic reagent in tau-mediated neurodegenerative disorder. Neuroscience 2008, Washington DC, Nov 15-20, 2008

8. Morinaga A, Hirohata M, Ono K, Yamada M. Estrogen exhibits anti-amyloidogenicity for β-amyloid fibrils in vitro. The 11th International Conference on Alzheimer’s Disease and Related Disorders (ICAD2008), Chicago, July 26-31, 2008

9. Morinaga A, Hirohata M, Ono K, Yamada M. Estrogen has anti-amyloidogenic effects on Alzheimer’s β-amyloid fibrils in vitro. International Symposium on Innovative Brain Science for Development, Learning, Memory and Autism, Kanazawa, July 17, 2008

10. Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB. Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. Twentieth Annual Neuroscience Poster Session In UCLA, Los Angeles, Dec 2, 2008

11. Samuraki M, Matsunari I, Chen W, Yajima K, Yanase D, Fujikawa A, Takeda N, Nishimura S, Matsuda H, Yamada M. Prevalence of reduced glucose metabolism or gray-matter concentration in healthy Apo E ε 4 carriers: The Ishikawa Brain Imaging Study. Annual Congress of the European Association of Nuclear Medicine, Munich, Oct 12-15, 2008 (EANM Eckert & Ziegler Abstract Award受賞)

12. Shima K, Matsunari I, Samuraki M, Shinohara M, Wei-Ping Chen, Yanase D, Ono K, Yoshita M, Yamada M. FDG PET in Relation to Atrophic Pattern Using Voxel-Based Morphometry in Patients with Alzheimer’s Disease. International Symposium on Innovative Brain Science for Development, Learning, Memory and Autism. Kanazawa, July 17-19 and Aug 8, 2008

13. Shima K, Matsunari I, Samuraki M, Wei-Ping Chen, Yanase D, Takeda N, Yoshita M, Nishimura S, Matsuda H, Yamada M. FDG PET in Relation to Atrophic Pattern Using Voxel-Based Morphometry in Patients with Alzheimer’s Disease, The Ishikawa Brain Imaging Study. Annual Congress of The European Association of Nuclear Medicine, Munich, Oct 11-15, 2008

14. Teplow DB, Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM. Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. Neuroscience 2008. Washington DC, Nov 15-20, 2008

15. Wang J, Ho L, Ono K, Zhao W, Qian XJ, Humala N, Teplow DB, Pasinetti G. Development of carvedilol as anti-Abeta oligomerization agent for the treatment of Alzheimer‘s disease. Neuroscience 2008. Washington DC, Nov 15-20, 2008

16. Yoshita M, Noto D, Takahashi K, Yamada M. 123-MIBG scintigraphy in PSP, CBD and IPD. 19th International Symposium of the American Autonomic Society. Kauai, Oct 29, 2008