2015

研究業績

Papers (English)

Original papers

1. Edahiro S, Maruta T, Negami M, Adachi Y, Yoshikawa H. Spectral analyses of heart rate variability by acceleration plethysmography for diagnostic support of migraine: clinical research. J Neurol Disord 3:229, 2015

2. Glazer H, Dong C, Yoshita M, Rundek T, Elkind MS, Sacco RL, DeCarli C,
Stern Y, Wright CB. Subclinical cerebrovascular disease inversely associates with learning ability: The NOMAS. Neurology 84:2362-2367, 2015

3. Hayashi K, Iwasa K, Morinaga A, Ono K, Yamada M. Exacerbation of myasthenia gravis by intravenous peramivir. Muscle Nerve 51:935-936, 2015

4. Ikeda T, Yoshizawa K, Takahashi K, Ishida C, Komai K, Kobayashi K, Sugiura S. Effectiveness of electric toothbrushing in patients with neuromuscular disability: A randomized observer-blind crossover trial. Spec Care Dentist (In Press)

5. Ishida C, Kobayashi K, Kitamura T, Ujike H, Iwasa K, Yamada M. Frontotemporal dementia with parkinsonism linked to chromosome 17 with the MAPT R406W mutation presenting with a broad distribution of abundant senile plaques. Neuropathology 35:75-82, 2015

6. Ishida N, Kobayashi E, Kondo Y, Matsushita R, Komai K. Pharmacokinetics and safety of 3,4-diaminopyridine base in healthy Japanese volunteers. Int J Clin Pharmacol Ther 53:674-680, 2015

7. Kobayashi A, Matsuura Y, Iwaki T, Iwasaki Y, Yoshida M, Takahashi H, Murayama S, Takao M, Kato S, Yamada M, Mohri S, Kitamoto T. Sporadic Creutzfeldt-Jakob disease MM1+2 and MM1 are identical in transmission properties. Brain Pathol (In Press)

8. Kobayashi A, Parch P, Yamada M, Brown P, Saveroni D, Matsuura Y,
Takeuchi A, Mohri S, Kitamoto T. Transmission properties of atypical Creutzfeldt-Jakob disease: a clue to disease etiology? J Virol 89:3939-3946, 2015 

9. Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S,
Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H,
Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White III CL, Wisniewski T, Woulfe JM, Yamada M, Dickson DW. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathol (In Press)

10. Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LPC, Gambetti P, Blevins J, Zhang S, Cohen Y,
Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TFJ, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haïk S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O’Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kähler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A,
Kraaij R, van Rooij JGJ, Ikram MA, Uitterlinden AG, van Duijn CM,
Exome Aggregation Consortium (ExAC), Daly MJ, MacArthur DG. Quantifying penetrance in a dominant disease gene using large population control cohorts. Sci Transl Med (In Press)

11. Murono S, Hamaguchi T, Yoshida H, Nakanishi Y, Tsuji A, Endo K, Kondo S, Wakisaka N, Yamada M, Yoshizaki T. Evaluation of dysphagia at the initnial diagnosis of amyltrophyic lateral sclerosis. Auris Nasus Larynx 42:213-217, 2015

12. Nakamura K, Hamaguchi T, Yamada M. Demyelinating polyneuropathy after long-term treatment with infliximab. Int J Rheum Dis (In Press)

13. Nakamura K, Mori F, Kon T, Tanji K, Miki Y, Tomiyama M, Kurotaki H, Toyoshima Y, Kakita A, Takahashi H, Yamada M, Wakabayashi K. Accumulation of phosphorylated α-synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration. Neuropathology (In Press)

14. Nakamura K, Mori F, Kon T, Tanji K, Miki Y, Tomiyama M, Kurotaki H, Toyoshima Y, Kakita A, Takahashi H, Yamada M, Wakabayashi K. Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwannian cytoplasmic inclusions) in multiple system atrophy. Acta Neuropathol Commun 3:29, 2015

15. Nakamura K, Mori F, Tanji K, Miki Y, Toyoshima Y, Kakita A, Takahashi H, Yamada M, Wakabayashi K. α-Synuclein pathology in the cranial and spinal nerves in Lewy body disease. Neuropathology (In Press)

16. Nakamura K, Mori F, Tanji K, Miki Y, Yamada M, Kakita A, Takahashi H, Utsumi J, Sasaki H, Wakabayashi K. Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in Lewy bodies. Neuropathology 35:432-440, 2015

17. Nakamura Y, Ae R, Takumi I, Sanjo N, Kitamoto T, Yamda M, Mizusawa H. Descriptive epidemiology of prion disease in Japan: 1999-2012. J Epidemiol 25:8-14, 2015

18. Noguchi-Shinohara M, Ono K, Hamaguchi T, Iwasa K, Nagai T, Kobayashi S, Nakamura H, Yamada M. Pharmacokinetics, safety and tolerability of Melissa officialis extract which contained rosmarinic acid in healghy individuals: a randomized controlled trial. PLoS One 10:e0126422, 2015

19. Nozaki I, Kato-Motozaki Y, Ikeda T, Takahashi K, Tagami A, Ishida C,
Komai K. Aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy treated with qing fei tang: two case reports. J Med Case Rep 9:67, 2015

20. Sakai K, Ikeda Y, Ishida C, Matsumoto Y, Ono K, Iwasa K, Yamada M. Inclusion body myositis with granuloma formation in muscle tissue. Neuromuscul Disord 25:706-712, 2015

21. Sakai K, Ishida C, Morinaga A, Takahashi K, Yamada M. Somatic sprouts and halo-like amorphous materials of the Purkinje cells in Huntington’s disease. Cerebellum 14:707-710, 2015

22. Samuraki M, Matsunari I, Yoshita M, Shima K, Noguchi-Shinohara M, Hamaguchi T, Ono K, Yamada M. Cerebral amyloid angiopathy-related microbleeds correlate with glucose metabolism and brain volume in Alzheimer’s disease. J Alzheimers Dis 48:517-528, 2015

23. Shima K, Iwasa K, Yoshita M, Yamada M. Vernet’s syndrome induced by internal jugular vein thrombosis. J Neurol Neurosurg Psychiatry (In Press)

24. Shimazaki C, Fuchida S-I, Suzuki K, Ishida T, Imai H, Sawamura M,
Takamatsu H, Abe M, Miyamoto T, Hata H, Yamada M, Ando Y. Phase 1 study of bortezomib in combination with melphalan and dexamethsone in Japanese patients with relapsed AL amyloidosis. Int J Hematol (In Press)

25. Takahashi K, Kakuda Y, Munemoto S, Yamazaki H, Nozaki I, Yamada M. Differentiation of donor-derived cells into microglia after umbilical cord blood stem cell transplantation. J Neuropathol Exp Neurol 74:862-866, 2015

26. Takahashi R, Ono K, Takamura Y, Mizuguchi M, Ikeda T, Nishijo H, Yamada M. Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity. J Neurochem 134:943-955, 2015

27. Takeuchi A, Kobayashi A, Parchi P, Yamada M, Morita M, Uno S, Kitamoto T. Distinctive properties of plaque-type dura mater graft-associated Creutzfeldt-Jakob disease in cell-protein misfolding cyclic amplification. Lab Invest (In Press)

28. Umeda T, Ono K, Klein WL, Yamada M, Mori H, Tomiyama T. Rifampicin is a candidate preventive medicine against amyloid β and tau oligomers. Brain (In Press)

29. Wright CB, Gardener H, Dong C, Yoshita M, DeCarli C, Sacco RL, Stern Y, Elkind MS. Infectious burden and cognitive decline in the Northern Manhattan Study. J Am Geriatr Soc 63:1540-1545, 2015

30. Yamaguchi K, Sakai K, Yamada M. Tracking rheumatoid leptomeningitis on diffusion-weighted MRI. Intern Med 54:1569-1570, 2015

31. Yoshita M, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakajima K, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Samuraki S, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamasaki J, Yamashina S, Yamada M. Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: A multicenter study. PLoS One 10:e0120540, 2015

32. Zekonyte J, Sakai K, Nicoll JA, Weller RO, Carare RO. Quantification of molecular interactions between apoE, amyloid-beta (Aβ) and laminin: Relevance to accumulation of Aβ in Alzheimer’s disease. Biochim Biophys Acta (In press)

Reviews

1. Kobayashi A, Parchi P, Yamada M, Mohri S, Kitamoto T. Neuropathological and biochemical criteria to identify acquired Creutzfeldt-Jakob disease among presumed sporadic cases. Neuropathology (In Press)

2. Kobayashi A, Teruya K, Matsuura Y, Shirai T, Nakamura Y, Yamada M, Mizusawa H, Mohri S, Kitamoto T. The influence of PRNP polymorphisms on human prion disease susceptibility: an update. Acta Neuropathol 130:159-170, 2015

3. Yamada M. Cerebral amyloid angiopathy: emerging concepts. J Stroke 17:17-30, 2015

4. Yamada M, Ono K, Hamaguchi T, Noguchi-Shinohara M. Natural phenolic compounds as thepeurtic and preventive agents for cerebral amyloidosis. Adv Exp Med Biol 863:79-94, 2015

Book

1. Yamada M, Ono K, Hamaguchi T, Noguchi-Shinohara M. Natural phenolic compounds as therapeutic and preventive agents for cerebral amyloidosis. In: Vassallo N ed. Advances in Experimental Medicine and Biology volume 863 Natural compounds as therapeutic agents for amyloidogenic diseases, Switzerland, Springer, pp79-94, 2015

Invited lectures

1. Hamaguchi T, Sakai K, Nozaki I, Noguchi-Shinohara M, Sanjo N, Nakamura Y, Kitamoto T, Murayama S, Satoh K, Harada M, Mizusawa H, Yamada M. Proposal of new diagnostic criteria for MM2-cortical type sporadic Creutzfeldt-Jakob disease. European CJD Surveillance Experts Meeting, Butapest, September 18, 2015

2. Sakai K, Boche D, Carare R, Johnston D, Holmes C, Love S, Nicoll J. Aβ immunothreapy for Alzheimer’s disease: effects on apolipoprotein E and cerebral vasculature. 7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2015 Tokyo), Tokyo, September 16-19, 2015

3. Yamada M. 123I-MIBG myocardinal scintigraphy for the diagnosis of dementia with Lewy bodies. The 9th International Congress of the Asian Society Against Dementia (ASAD), Kumamoto, September 14-16, 2015

4. Yamada M, Samuraki M, Yoshita M, Shima K, Noguchi-Shinohara M, Hamaguchi T, Ono K, Matsunari I. Cerebral amyloid angiopathy in Alzheimer’s disease. 7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2015 TOKYO), Tokyo, September 16-19, 2015

5. Yamada M. Clinical-Neuroimaging-Pathology Symposium: A 78-year-old woman with the clinical diagnosis of possible DLB. International Dementia with Lewy Bodies Conference, Fort Lauderdale, December 1-4, 2015

Presentations

1. Furukawa F, Sanjo N, Higuma M, Kitamoto T, Hizume M, Nakamura Y, Tsukamoto T, Murayama S, Koshi K, Matsukawa T, Tsuji S, Goto J, Yamada M, Mizusawa H, Yokota T. Clinical features in Gerstmann-Sträussler-Scheinker syndrome with P105L mutation. PRION 2015, Fort Collins, May 26-29, 2015

2. Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T. Amyloid β42 deposition in the brain of the GSS with the P105L mutation. Asian Pacific Prion Symposium 2015, Kanazawa, September 4-5, 2015

3. Hamaguchi T, Sakai K, Noguchi-Shinohara M, Nozaki I, Takumi I, Sanjo N, Nakamura Y, Kitamoto T, Saito N, Mizusawa H, Yamada M. A comparative study of dura mater graft-associated Creutzfeldt-Jakob disease between Japan and other countries. PRION 2015, Fort Collins, May 26-29, 2015

4. Hamaguchi T, Sakai K, Nozaki I, Noguchi-Shinohara M, Sanjo N, Nakamura Y, Kitamoto T, Murayama S, Satoh K, Harada M, Mizusawa H, Yamada M. Clinical diagnosis of MM2-cortical type sporadic Creutzfeldt-Jakob disease. Asian Pacific Prion Symposium 2015, Kanazawa, September 4-5, 2015

5. Kobayashi A, Yamada M, Matsuura Y, Mohri S, Kitamoto T. Neuropathological and biochemical criteria to identify acquired Creutzfeldt-Jakob disease among presumed sporadic cases. Asian Pacific Prion Symposium 2015, Kanazawa, September 4-5, 2015

6. Komai K, Tagami A, Ishida C, Takahashi K, Motozaki Y, Ikeda Y, Yoshida M, Kirisaki H, Okano Y. Multidisciplinary respiratory care support team improves respiratory management of inpatients with amyotrophic lateral sclerosis. 26th International Symposium on ALS/MND, Orlando, December 11-13, 2015

7. Ono K, Takasaki J-I, Takahashi R, Ikeda T, Yamada M. Effects of antiparkinsonian agents on β-amyloid and α-synuclein oligomer formarion in vitro. Neuroscience 2015, Chicago, December 17-21, 2015

8. Minikel EV, Vallabh SM, Lek M, Estrada KO, Samocha E, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LPC, Gambetti P, Blevins J, Zhang S, Cohen Y,
Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TFJ, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haïk S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, O’Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kähler A, Chambert K, McCarroll S, Sullivan PF, HultmanCM, Purcell SM, Sklar P,
van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JGJ, Iklam MA, Uitterlinden AG, van Duijn CM, Exome Aggregation Consortium(ExAC), Daly MJ, MacArthur DG. Assessing the pathogenicity of rare PRNP variants by comparing case and control allele frequency. PRION 2015, Fort Collins, May 26-29, 2015

9. Miyashita M, Takada M, Nishio A, Ikai S, Yoshikawa H, Matsuura K, Hayashi F, Adachi Y, Sado T, Horita R, Yamamoto M. Need for education on pregnancy, infertility, and menstruation for High School and University student’s life plan regarding marriage and maternity. 11th ICM Asia Pacific Regional conference 2015, Yokohama, July 20-22, 2015

10. Murai M, Nakamura Y, Kitamoto T, Tsuboi Y, Sanjyo N, Yamada M,
Mizusawa H, Kira JI. Clinical and epidemiclogical survey of Gerstmann-Sträussler-Scheinker desease with codon 102 mutation in Japan.
XXII World Congress of Neurology, Santiago, October 31-November 5, 2015

11. Sakai K, Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Takumi I, Sanjo N, Nakamura Y, Kitamoto T, Saito N, Mizusawa H, Yamada M. Sensory disturbance in Creutzfeldt-Jakob disease: a comparative study of the sporadic and dura mater graft-associated cases. Asian Pacific Prion Symposium 2015, Kanazawa, September 4-5, 2015

12. Sakai K, Boche D, Carare R, Johnston D, Hoimes C, Love S, Nicoll JA.
Aβ immunotherapy for Alzheimer’s disease: Effects on apolipoprotein E and cerebral vasculature. 7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2015 TOKYO), Tokyo, September 16-19, 2015

13. Sanjo N, Tsukamoto T, Furukawa F, Higuma M, Hizume M, Nakamura Y,
Satoh K, Kitamoto T, Yamada M, Yokota T, Mizusawa H. Human prion diasese in Japan: A prospective surveillance from 1999. XXII World Congress of Neurology, Santiago, October 31-November 5, 2015

14. Shinohara M, Ono K, Hamaguchi T, Iwasa K, Kobayashi S, Nagai T,
Nakamura H, Yamada M. Pharmacokinetics, Safety and tolerability of Melissa officials extract which contained rosmarinic acid in healthy individuals. Alzheimer’s Association International Conference (AAIC) 2015, Washinton, D.C., July 18-23, 2015

15. Takahashi K, Komai K, Ishida C, Motozaki Y, Ikeda T, Ikeda Y. Multiple sclerosis with idiopathic alopecia areata. 1st Congress of the European Academy of Neurology, Berlin, June 20-23, 2015

16. Takahashi K, Kakuda Y, Munemoto S, Yamazaki H, Nozaki I, Yamada M. Umbilical cord blood stem cells-derived microglia. XII European Meeting on Glial Cells in Health and Disease, Bilbao, July 15-18, 2015

17. Takeuchi A, Kobayashi A, Parchi P, Yamada M, Morita M, Uno S, Kitamoto T. Cell-PMCA of acquired Creutzfeldt-Jakob disease. Asian Pacific Prion Symposium 2015, Kanazawa, September 4-5, 2015

18. Tsukamoto T, Sanjo N, Hamaguchi T, Nakamura Y, Kitamoto T, Yamada M, Mizusawa H, Prion Disease Surveillance Committee, Japan. CJD with M232R: Its clinicopathological features. Asian Pacific Prion Symposium 2015, Kanazawa, September 4-5, 2015

19. Yamada M, Yoshita M, Arai H, Arai H, Asada T, Hanyu H, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizuno Y, Mori E, Nakajima K, Nakamura H, Nakano S, Nakashima K, Orimo S, Samuraki N, Takahashi A, Taki J, Tokuda T,
Urakami K, Utsumi K, Washimi Y, Yamasaki J, Yamashina S, Co-investigators of the DLB Diagnosis Study Group. The first multicenter study of 123I-meta-iodobenzylguanidine myocardial scintigraphy for the diagnosis of dementia with Lewy bodies. International Dementia with Lewy Bodies Conference, Fort Lauderdale, December 1-4, 2015

20. Yoshita M, Odake Y, Hosokawa M, Ikeda M, Ichikawa S, Sakamoto H. 123I-FP-CIT SPECT and 123I-MIBG scintigraphy between Lewy body disease and other neurodegenerative disorders. The 12th International Conference on Alzheimer’s & Parkinson’s Diseases, Nice, March 18-22, 2015

21. Yoshita M, Tsuji S, Yokoyama K, Sakamoto H. Clinical features of patients with suspected non-Alzheimer pathology (SNAP). XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function, Vancouber, June 27-30, 2015