研究業績

2012

Papers (English)

 
Original papers


1. Alcalde-Cabero E, Almazán-Isla J, Brandel JP, Breithaupt M, Catarino J, Collins S, Haybäck J, Höftberger R, Kahana E, Kovacs GG, Ladogana A, Mitrova E, Molesworth A, Nakamura Y,
Pocchiari M, Popovic M, Ruiz-Tovar M, Taratuto AL, van Duijn C, Yamada M, Will RG, Zerr I,
de Pedro-Cuesta J. Health professions and risk of sporadic Creutzfeldt-Jakob disease, 1965 to 2010. Euro Surveill 17:pii:20144, 2012

2. Fujita K, Harada M, Sasaki M, Yuasa T, Sakai K, Hamaguchi T, Sanjo N, Shiga Y, Satoh K, Atarashi R, Shirabe S, Nagata K, Maeda T, Murayama S, Izumi Y, Kaji R, Yamada M, Mizusawa H. Multicentre, multiobserver study of diffusion-weighted and fluid-attenuated inversion recovery MRI for the diagnosis of sporadic Creutzfeldt-Jakob disease: a reliability and agreement study. BMJ Open 2:e000649, 2012

3. Furukawa Y, Komai K, Ishida C, Takahashi K, Tagami A, Motozaki Y, Ikeda T. Cause of death in Japanese patients with amyotrophic lateral sclerosis on tracheostomy-positive pressure ventilation. Eur Neurol 68:261-263, 2012

4. Hamaguchi T, Eisele YS, Varvel NH, Lamb BT, Walker LC, Jucker M. The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain. Acta Neuropathol 123:31-37, 2012

5. Hamano T, Mutoh T, Hirayama M, Uematsu H, Higuchi I, Koga H, Umehara F, Komai K, Kuriyama M. Winged scapula in patients with myotonic dystrophy type 1. Neuromuscul Disord 22:755-758, 2012

6. Higuma M, Sanjo N, Satoh K, Shiga Y, Sakai K, Nozaki I, Hamaguchi T, Nakamura Y,
Kitamoto T, Shirabe S, Murayama S, Yamada M, Tateishi J, Mizusawa H. Relationships between clinicopathological features and cerebrospinal fluid biomarkers in Japanese patients with genetic prion diseases. PLoS One (In Press)

7. Hirohata M, Ono K, Takasaki J-I, Takahashi R, Ikeda T, Morinaga A, Yamada M. Anti-amyloidogenic effects of soybean isoflavones in vitro: fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils. Biochem Biophys Acta-Mol Basis Dis 1822:1316-1324, 2012

8. Imai T, Tsuda E, Hozuki T, Yoshikawa, H, Yamauchi R, Saitoh M, Hisahara S, Motomura M, Kawamata J, Shimohama S. Contribution of anti-ryanodine receptor antibody to impairment of excitation-contraction coupling in myasthenia gravis. Clin Neurophysiol 123:1242-1247, 2012

9. Imai T, Tsuda E, Hozuki T, Yamauchi R, Saitoh M, Hisahara S, Yoshikawa H, Motomura M, Kawamata J, Shimohama S. Early effect of tacrolimus in improving excitation-contraction coupling in myasthenia gravis. Clin Neurophysiol 123:1886-1890, 2012

10. Kobayashi S, Yokoyama S, Maruta T, Negami M, Muroyama A, Mitsumoto Y, Iwasa K,
Yamada M, Yoshikawa H. Autoantibody-induced internalization of nicotinic acetylcholine receptor α3 subunit exogenously expressed in human embryonic kidney cells. J Neuroimmunol (In Press)

11. Miyasaka N, Hara M, Koike T, Saito E, Yamada M, Tanaka Y. Effects of intravenous immunoglobulin therapy in Japanese patients with polymyositis and dermatomyositis resistant to corticosteroids: a randomized double-blind placebo-controlled trial. Mod Rhuematol 22:382-393, 2012

12. Nakajima K, Okuda K, Matsuo S, Yoshita M, Taki J, Yamada M, Kinuya S. Standardization of metaiodobenzylguanidine heart-to-mediastinum ratio using a calibration phantom: effects of correction on normal databases and a multi-center study. Eur J Nucl Med Mol Imaging 39:113-119, 2012

13. Nakamichi K, Mizusawa H, Yamada M, Kishida S, Miura Y, Shimokawa T, Takasaki T, Lin C-K, Kurane I, Saijo M. Characteristics of progressive multifocal leukoencephalopathy clarified through internet-assisted laboratory surveillance in Japan. BMC Neurol 12:121, 2012

14. Nozaki I, Kato-Motozaki Y, Ikeda T, Takahashi K, Tagami A, Ishida C, Komai K. Clinical features in association with neurodegenerative diseases and malignancies. Eur Neurol (In Press)

15. Nozaki I, Sakai K, Kitamoto T, Yamada M. Reply to “the Letter to the Editor: Beck et al. Prion protein gene M232R variation is probably uncommon polymorphism rather than a cause of inherited prion disease” for “Nozaki et al. Prospective 10-year surveillance of human prion disease in Japan (Brain 2010; 133: 3043-3057).” Prion protein gene M232R mutation as a cause of genetic prion disease. Brain 135:e210, 2012

16. Nozaki I, Yamada M. An easy diagnositic tool distinguishing lateral medullary infarction from peripheral vertigo. Clin Neurol Neurosurg 114:68-69, 2012

17. Ono K, Li L, Takamura Y, Yoshiike Y, Zhu L, Han F, Mao X, Ikeda T,Takasaki J-I, Nishijo H, Takashima A, Teplow DB, Zagorski MG, Yamada M. Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site specific binding. J Biol Chem 287:14631-14643, 2012

18. Ono K, Mochizuki H, Ikeda T, Nihira T, Takasaki J-I, Teplow DB, Yamada M. Effect of melatonin on α-synuclein self-assembly and cytotoxicity. Neurobiol Aging 33:2172-2185, 2012

19. Ono K,* Takahashi R,* Ikeda T, Yamada M. Cross-seeding effects of amyloid β-protein and α-synuclein. J Neurochem 122:883-890, 2012 *Equally contributed.

20. Rosen RF, Fritz JJ, Dooyema J, Cintron AF, Hamaguchi T, Lah JJ, LeVine ⅢH, Jucker M,
Walker LC. Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats. J Neurochem 120:660-666, 2012

21. Sakai K, Hayashi S, Sanpei K, Yamada M, Takahashi H. Multiple cerebral infarcts with a few vasculitic lesions in the chronic stage of cerebral amyloid angiopathy related inflammation. Neuropathology 32:551-556, 2012

22. Sakai K, Ono K, Harada H, Shima K, Notoya M, Yamada M. Parkinson’s disease showing progressive conduction aphasia. Neurol Sci 33:399-402, 2012

23. Samuraki M, Matsunari I, Chen W-P, Shima K, Yanase D, Takeda N, Matsuda H, Yamada M. Glucose metabolism and gray-matter concentration in apolipoprotein E ε4 positive normal subjects. Neurobiol Aging 33:2321-2323, 2012

24. Shima K, Matsunari I, Samuraki M, Chen W-P, Yanase D, Noguchi-Shinohara M, Takeda N, Ono K, Yoshita M, Miyazaki Y, Matsuda H, Yamada M. Posterior cingulate atrophy and metabolic decline in early stage Alzheimer’s disease. Neurobiol Aging 33:2006-2917, 2012

25. Sugano K, Yokogawa M, Yuki S, Dohmoto C, Yoshita M, Hamaguchi T, Yanase D, Iwasa K,
Komai K, Yamada M. Effect of cognitive and aerobic training intervention for older adults with mild or no cognitive impairment: a derivative study of the Nakajima Project. Dement Geriatr Cogn Dis Extra 2:69-80, 2012

26. Takahashi K, Tanaka K. Clinical and magnetic resonance imaging features of multiple sclerosis with autoreactive antibodies in Ishikawa Prefecture, Japan. J Neuroimmunol 250:11-14, 2012

27. Takahashi R, Ikeda T, Hamaguchi A, Iwasa K, Yamada M. Coenzyme Q10 therapy in hereditary motor sensory neuropathy type VI with novel mitofusin 2 mutation. Intern Med 51:791-793, 2012

28. Takahashi R, Ono K, Ikeda T, Akagi A, Noto D, Nozaki I, Sakai K, Asakura H, Iwasa K,
Yamada M. Coagulation and fibrinolysis abnormalities in familial amyloid polyneuropathy. Amyloid 19:129-132, 2012

29. Takamori M, Nakamura T, Motomura M. Antibodies against Wnt receptor of muscle-Specific tyrosine kinase in myasthenia gravis. J Neuroimmunol(In Press)

30. Wang J, Ferruzzi MG, Ho L, Blount J, Janle EM, Gong B, Pan Y, Gowda GA, Raftery D,
Arrieta-Cruz I, Sharma V, Cooper B, Lobo J, Simon JE, Zhang C, Cheng A, Qian X, Ono K,
Teplow DB, Pavlides C, Dixon RA, Pasinetti GM. Brain-targeted proanthocyanidin metabolites for Alzheimer’s disease treatment. J Neurosci 32:5144-5150, 2012

31. Yoshikawa Y, Horiuchi M, Ishiguro N, Kadohira M, Kai S, Mizusawa H, Nagata C, Onodera T, Sata T, Tsutsui T, Yamada M, Yamamoto S. Alternative BSE risk assessment methodology of imported beef and beef offal to Japan. J Vet Med Sci 74:959-968, 2012

 
Reviews



1. Ono K, Yamada M. Vitamin A and Alzheimer’s disease. Geriatr Gerontol Int 12:180-188, 2012

2. Takamori M. Structure of the neuromuscular junction: function and cooperative mechanisms in the synapse. Ann N Y Acad Sci 1274:14-23, 2012

3. Yamada M. Predicting cerebral amyloid angiopathy-realated intracerebral hemorrhages and other cerebrovascular disorders in Alzheimer’s disease. Front Neurol 3:64, 2012
 
Book


1. Rosensweig C, Ono K, Murakami K, Lowenstein DK, Bitan G, Teplow DB. Preparation of stable amyloid β-protein oligomers of defined assembly order. In: Sigurdsson EM, Calero M, Gasset M, Methods in Molecular Biology 849 Amyloid Proteins. Human Press, New York, pp23-31, 2012

2. Yamada M, Naiki H. Cerebral amyloid angiopathy. In: Teplow DB ed. Progress in Molecular Biology and Translational Science, vol. 107. Molecular Biology of Neurodegenerative Diseases. Elsevier, Amsterdam, pp41-78, 2012
 

Presentations (International meeting)



 
Invited lectures




1. Ono K. Low order-oligomers as therapeutic targets of Alzheimer’s disease. Neuroscience Seminar in University of British Columbia, Vancouver, July 17, 2012

2. Takamori M. Structure of the neuromuscular junction: function and cooperative mechanisms in the synapes. New York Academy of Sciences: 12th International Conference on Myasthenia Gravis and Related Disorders, New York, May 21-23, 2012

3. Yamada M. Protein aggregation as a therapeutic target of cerebral amyloidosis.
Clinical Neuroscience Seminar, the University of Southampton, Southampton, May 8, 2012
 
Presentations




1. Arai T, Arai M, Itokawa M, Yoshida M, Tamaoka A, Kobayashi Z, Hosokawa M, Hasegawa M, Nonaka T, Tsuji H, Yamada M, Matsui M, Kaji R, Nakajima K, Kawano R, Takahashi S, Asada T, Akiyama H. Screening of the SOD1, TARDBP and FUS mutations and the pathological studies in Japanese cases with familial and sporadic amyotrophic lateral sclerosis. Alzheimer’s Association International Conference 2012, Vancouver, July 14-19, 2012

2. Hirohata M, Ono K, Takasaki J, Yamada M. Anti-amyloidogenic effects of isoflavones in vitro: fluorescence spectroscopy demonstrating direct interractions between isoflavones and Aβs. Alzheimer’s Association International Conference 2012, Vancouver, July 14-19, 2012

3. Iwasa K, Kato-Motozaki Y, Furukawa Y, Maruta T, Ishida C, Yoshikawa H, Yamada M. Up-regulation of MHC class I and class II in the skeletal muscles of myasthenia gravis. 12th International Conference on Myasthenia Gravis and Related Disorders, New York, May 21-23, 2012

4. Komai K, Matsushita R, Kondo Y, Ishida N, Ishida C. Pharmacokinetics of 3,4-diaminopyridine in healthy volunteers and a LEMS case. 13th Asia Oceanian Congress of Neurology, Melbourne, June 4-8, 2012

5. Matsunari I, Samuraki M, Shima K, Wei-Ping Chen, Noguchi-Shinohara M, Ono K, Yoshita M, Miyazaki Y, Matsuda H, Yamada M. Hippocampal glucose metabolism is reduced in some, but not all patients with Alzheimer’s disease: the Ishikawa brain imaging study. Annual Congress of the European Association of Nuclear Medicine, Milan, October 27-31, 2012

6. Noguchi-Shinohara M, Hamaguchi T, Nozaki I, Sakai K, Yamada M. Serum tau protein as a marker for the diagnosis of Creutzfeldt-Jakob disease. Asian Pacific Prion Symposium 2012, Yokohama, July 29-30, 2012

7. Ono K, Takasaki J, Yoshiike Y, Hirohata M, Ikeda T, Morinaga A, Takashima A, Yamada M. Vitamin A has anti-oligomerization effects on amyloid-β in vitro. Alzheimer’s Association International Conference on Alzheimer’s Disease 2012, Vancouver, July 14-19, 2012

8. Sakai K, Boche D, Love S, Nicoll J. Cerebral amyloid angiopathy-associated vasculopathy after Aβ immunotherapy for Alzheimer’s disease. Alzheimer’s Research UK Conference 2012, Birmingham, March 27-28, 2012

9. Sakai K, Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Sato T, Takumi I, Sanjo N,
Nakamura Y, Kitamoto T, Saito N, Mizusawa H, Yamada M. Prion protein propagation in dura mater graft-associated Creutzfeldt-Jakob disease. Prion 2012, Amsterdam, May 10-12, 2012

10. Sakai K, Boche D, Love S, Nicoll J. Cerebral amyloid angiopathy-associated vasculopathy after Aβ immunotherapy for Alzheimer’s disease. 10th European Congress of Neuropathology, Edinburgh, June 6-9, 2012

11. Sakai K, Hamaguchi T, Noguchi-Shinohara M, Nozaki I, Sato T, Takumi I, Sanjo N,
Nakamura Y, Kitamoto T, Saito N, Mizusawa H, Yamada M. Prion protein propagation in dura mater graft-associated Creutzfeldt-Jakob disease. Asian Pacific Prion Symposium 2012, Yokohama, July 29-30, 2012

12. Sakai K, Boche D, Love S, Nicoll J. Cerebral amyloid angiopathy-associated vasculopathy after Aβ immunotherapy for Alzheimer’s disease. 10th Annual Southampton Neuroscience Group (SoNG) Meeting, Southampton, September 20, 2012

13. Sakai K, Boche D, Love S, Nicoll J. Cerebral amyloid angiopathy-associated vasculopathy after Aβ immunotherapy for Alzheimer’s disease. 3rd International CAA Conference, Leiden, October 24-26, 2012

14. Sakajiri K, Nitta E. A retrospective study of cerebral venous sinus thrombosis (CVST). 13th Asian Oceanian Congress of Neurology, Melbourne, June 4-8, 2012

15. Sanjo N, Ohara M, Satoh K, Hamaguchi T, Nakamura Y, Kitamoto T, Yamada M, Mizusawa H. Clinical features of genetic prion disease and cerebrospinal fluid findings in Japanese patients. Prion 2012, Amsterdam, May 10-12, 2012

16. Sanjo N, Nakamura Y, Kitamoto T, Yamada M, Hamaguchi T, Moriwaka F, Aoki M, Kuroiwa Y, Nishizawa M, Takeda M, Inuzuka T, Abe K, Murai H, Murayama S, Satoh K, Harada M, Saito N, Takumi I, Mizusawa H. Human prion diseases in Japan: aprospective surveillance from 1999. Asian Pacific Prion Symposium 2012, Yokohama, July 29-30, 2012

17. Takahashi K, Tanaka K. Frequency and distribution of autoreactive antibodies between multiple sclerosis and neuromyelitis optica. Federation of Clinical Immunology Societies (FOCIS) 2012, Vancouver, June 20-23, 2012

18. Takahashi K, Miyake S, Kitamura K, Endo M. An increased expression of osteopontin in autoimmune T cells derived from multiple sclerosis. 8th FENS forum of Neuroscience, Barcelona, July 14-18, 2012

19. Takahashi K, Tanaka K. Frequency and distribution of autoreactive antibodies between multiple sclerosis and neuromyelitis optica in Japan. 16th EFNS congress, Stockholm, September 8-11, 2012

20. Wang J, Ono K, Yamada M, Rosenberg P, Pasinetti GM. Repurposing antihypertensive drugs for Alzheimer’s disease. Alzheimer’s Association International Conference 2012, Vancouver, July 14-19, 2012

21. Wright C, Dong C, Yoshita, M, Disla N, Elkind M, DeCarli C, Sacco R, Rundek T. Asymptomatic internal carotid artery stenosis is associated with more cortical subclinical brain infarcts: the Northern Manhattan Study (NOMAS). International Stroke Conference 2012, New Orleans, February 1-3, 2012

22. Yamamoto M, Yoshikawa H, Adachi Y. Student health care on campuses in Japan: the approach to care for the Japanese college student. ACHA 2012 Annual Meeting, Chicago, May 28-June 1, 2012

23. Yoshita M, Ichikawa S, Sakamoto H, Odake Y, Tobe T, Furuta H. Upward gaze limitation in dementia with Lewy bodies and Alzheimer’s type dementia. Alzheimer’s Association International Conference 2012, Vancouver, July 14-19, 2012
 
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